Unit of Nephrology, Dialysis and Transplantation, IRCCS Foundation Policlinico San Matteo of Pavia, Italy
Maria Antonietta Grignano is a dedicated biologist and clinical researcher at the Unit of Nephrology, Dialysis, and Transplantation at Fondazione IRCCS Policlinico San Matteo di Pavia, Italy. With specialization in clinical pathology and clinical biochemistry, she has significantly contributed to translational nephrology research, focusing on extracellular vesicles, ischemic damage, and innovative drug delivery strategies. Her work bridges molecular biology and clinical application, aiming to improve outcomes in kidney transplantation and chronic kidney disease.
Publication Profile
🎓 Education Background:
Maria holds a Bachelor’s Degree in Biological Sciences from the University of Palermo (2006–2010), followed by a Master’s Degree in Experimental and Applied Biology from the University of Pavia (2010–2012). She further specialized in Clinical Biochemistry and Clinical Pathology at the University of Pavia from 2017 to 2021, gaining advanced expertise in clinical and diagnostic research.
💼 Professional Experience:
Since 2014, Maria has been an integral part of the Fondazione IRCCS Policlinico San Matteo, contributing first as a research fellow, then under various research contracts, and eventually as the head of the Research Laboratory within the Nephrology Unit. Between 2018 and 2019, she researched virus-specific antibody responses in transplant patients, and earlier, she also worked in pediatric hematology oncology. Her current role since December 2019 as a lead researcher reflects her long-term dedication to advancing nephrology through laboratory-based innovation.
🏆 Awards and Honors:
While specific awards and honors are not listed publicly, Maria’s continuous appointments at one of Italy’s top clinical research institutes, her leadership of multiple innovative projects, and her extensive publication record in high-impact journals underscore her recognition and credibility in the nephrology research community.
🔬 Research Focus:
Maria’s research revolves around the therapeutic potential of extracellular vesicles derived from mesenchymal stem cells, particularly in reducing ischemia-reperfusion injury during kidney transplantation. She is also exploring the modulation of immune responses in chronic kidney disease, including the effect of PCSK9 inhibitors, and has participated in projects correlating transcriptional profiles with response to extracorporeal photo-apheresis. Her projects integrate advanced bioengineering, clinical immunology, and proteomics.
🧾 Conclusion:
Maria Antonietta Grignano exemplifies scientific commitment and clinical relevance through her research in nephrology and transplantation. Her work in cellular therapies and biomarker discovery not only advances the field but also holds promise for patient-specific interventions and improved transplant outcomes.
📚 Top Publications :
Engineered ATP-Loaded Extracellular Vesicles Derived from Mesenchymal Stromal Cells: A Novel Strategy to Counteract Cell ATP Depletion in an In Vitro Model
International Journal of Molecular Sciences, 2025
Cited by: Ongoing
Atypical Hemolytic Uremic Syndrome Associated with BNT162b2 mRNA COVID-19 Vaccine in a Kidney Transplant Recipient: A Case Report and Literature Review
Infectious Disease Reports, 2025
Cited by: Ongoing
The Impact of Serum/Plasma Proteomics on SARS-CoV-2 Diagnosis and Prognosis
International Journal of Molecular Sciences, 2024
Cited by: Ongoing
Characterization of Mesenchymal Stromal Cells after Serum Starvation for Extracellular Vesicle Production
Applied Sciences, 2024
Cited by: Ongoing
Uremic plasma proteins accumulate in peripheral blood mononuclear leukocytes inducing apoptosis: insights in the immuno-proteostasis response of chronic kidney disease
ResearchSquare, 2023
Cited by: Ongoing